According to the teaching and therapy method of Univ. Prof. Dr. Augustinus Bader reports that there are 2 fundamental and medically unexplained fundamental epigenetic regulatory mechanisms related to trauma and aging associated with endogenous stem cell communication processes. With the discovery of these special regulatory mechanisms based on 3 key interacting processes (A, B, and C) explain these differences in the healing process. Prof. Bader has developed a therapeutic principle that uses the communication mechanisms of endogenous stem cells to utilize preventive and regenerative repair principles of the body in the case of major defects or aging processes.